The management of measuring instruments and testing instruments is one of the important basic management work of modern enterprises, and is also a powerful guarantee to protect the interests of enterprises. It is also a major measure to ensure the performance and accuracy of measuring instruments. The verification of measuring instruments and testing instruments is divided into national compulsory verification and calibration. For enterprises, most of the testing instruments belong to the scope of calibration. Due to the different product technical requirements of each enterprise, the testing instruments involved are relatively special, and the amount of use in industry is relatively small. In addition, the technical characteristics, use conditions, use methods, working principles and other external professional verification institutions are not familiar with them, It often causes the calibration and preparation results of the testing instruments to fail to meet the requirements, and raises objections in the third-party qualification review of the enterprise. For this reason, whether enterprises can carry out self-calibration according to the working principle of special testing instruments is discussed in this paper